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pentobarbital will lessen the level or impact of dienogest/estradiol valerate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Gals should not choose estradiol valerate/dienogest as their contraceptive even though working with robust CYP3A4 inducers on account of prospective lessen in contraceptive efficacy.Variable; aff

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